Selective inhibition by vasocortin of histamine release induced by dextran and concanavalin-A from rat peritoneal cells.
Br J Pharmacol
; 98(1): 32-4, 1989 Sep.
Article
em En
| MEDLINE
| ID: mdl-2478246
ABSTRACT
Vasocortin, a glucocorticoid-induced anti-inflammatory protein, has been purified from the peritoneal lavage fluid of dexamethasone-treated rats. Vasocortin inhibited the release of histamine from rat peritoneal cells stimulated by dextran or concanavalin A but did not alter the release induced by calcium ionophore A23187 or compound 48/80. This selective effect exhibited by vasocortin mimics the glucocorticoid inhibition of histamine release from rat mast cells.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas
/
Dextranos
/
Concanavalina A
/
Liberação de Histamina
/
Mastócitos
/
Anti-Inflamatórios
Limite:
Animals
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article