Filaggrin-insufficiency in keratinocytes influences responsiveness of allergen-specific T cells to cognate antigen and compounds barrier function deficiency.

Marwah, Ishita; Wang, Xinwen; Chan, Hsien; Ogg, Graham S; Gutowska-Owsiak, Danuta

Marwah, Ishita; Wang, Xinwen; Chan, Hsien; Ogg, Graham S; Gutowska-Owsiak, Danuta.

Afiliação

Marwah I; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Wang X; Department of Periodontology and Oral Medicine, School of Stomatology, The Fourth Military Medical University, Xi'an, China.
Chan H; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Ogg GS; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Gutowska-Owsiak D; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. Electronic address: danuta.gutowska-owsiak@ndm.ox.ac.uk.

Clin Immunol ; 153(1): 153-5, 2014 Jul.

Article em En | MEDLINE | ID: mdl-24786917

Assuntos

Alérgenos/imunologia; Proteínas de Filamentos Intermediários/genética; Queratinócitos/metabolismo; Linfócitos T/imunologia; Linfócitos T/metabolismo; Proteínas Filagrinas; Humanos; Proteínas de Filamentos Intermediários/deficiência; Pele/imunologia; Pele/metabolismo; Pele/patologia

Palavras-chave

Antigen-experienced T cells; Der p 1; Filaggrin; House dust mite; Skin barrier

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alérgenos / Linfócitos T / Queratinócitos / Proteínas de Filamentos Intermediários Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google