A new triterpenoid saponin and an oligosaccharide isolated from the fruits of Sapindus mukorossi.
Nat Prod Res
; 28(14): 1058-64, 2014.
Article
em En
| MEDLINE
| ID: mdl-24800793
ABSTRACT
A new triterpenoid saponin (1) and a new oligosaccharide (2), together with three known saponins (3-5), have been isolated from n-BuOH extract of the fruits of Sapindus mukorossi Gaertn. The structures were elucidated using detailed analysis of one- and two-dimensional nuclear magnetic resonance spectra along with their mass spectrometric data and the results of acid hydrolysis. Of the isolated compounds 1 and 3-5 displayed cytotoxic effects against human cancer cell lines in A-549 (lung carcinoma), MDA-231 (breast carcinoma) and PC-3 (prostatic carcinoma).
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácido Oleanólico
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Oligossacarídeos
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Saponinas
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Triterpenos
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Medicamentos de Ervas Chinesas
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Sapindus
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Frutas
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Antineoplásicos Fitogênicos
Limite:
Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article