In utero exposure to selective serotonin reuptake inhibitors and risk for autism spectrum disorder.
J Autism Dev Disord
; 44(10): 2558-67, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-24803368
ABSTRACT
We investigated whether there is an association between increased risk for autism spectrum disorders (ASD) and selective serotonin reuptake inhibitors (SSRIs) used during pregnancy. This study used Denmark's health and population registers to obtain information regarding prescription drugs, ASD diagnosis, and health and socioeconomic status. There were 1.5 % of cases and 0.7 % of controls exposed to SSRIs during the pregnancy period, and higher effect estimates observed with longer use. We found evidence that in utero exposure to SSRIs increases a child's risk associated with ASD. These results, while adding to the limited knowledge on prenatal pharmacological exposures as potential ASD risk factors, need to be balanced against the benefits of indicated medication use by pregnant mothers.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Efeitos Tardios da Exposição Pré-Natal
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Transtornos Globais do Desenvolvimento Infantil
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Inibidores Seletivos de Recaptação de Serotonina
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Observational_studies
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Risk_factors_studies
Limite:
Adult
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Child
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Female
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Humans
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Male
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Middle aged
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Pregnancy
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article