FZD1 activates protein kinase C delta-mediated drug-resistance in multidrug-resistant MES-SA/Dx5 cancer cells.

Hung, Tsai-Hsien; Chen, Chuan-Mu; Tseng, Ching-Ping; Shen, Chih-Jie; Wang, Hui-Ling; Choo, Kong-Bung; Chong, Kowit Yu

Hung, Tsai-Hsien; Chen, Chuan-Mu; Tseng, Ching-Ping; Shen, Chih-Jie; Wang, Hui-Ling; Choo, Kong-Bung; Chong, Kowit Yu.

Afiliação

Hung TH; Graduate Institute of Biomedical Sciences, Division of Biotechnology College of medicine, Chang Gung University,Tao-Yuan, Taiwan, Republic of China.
Chen CM; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan, Republic of China.
Tseng CP; Graduate Institute of Biomedical Sciences, Division of Biotechnology College of medicine, Chang Gung University,Tao-Yuan, Taiwan, Republic of China; Department of Medical Biotechnology and Laboratory Science, College of medicine, Chang Gung University, Tao-Yuan, Taiwan, Republic of China; Molecular
Shen CJ; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan, Republic of China.
Wang HL; Department of Medical Biotechnology and Laboratory Science, College of medicine, Chang Gung University, Tao-Yuan, Taiwan, Republic of China.
Choo KB; Department of Preclinical Sciences, Faculty of Medicine and Health Sciences and Centre for Stem Cell Research, Universiti Tunku Abdul Rahman, Selangor, Malaysia.
Chong KY; Graduate Institute of Biomedical Sciences, Division of Biotechnology College of medicine, Chang Gung University,Tao-Yuan, Taiwan, Republic of China; Department of Medical Biotechnology and Laboratory Science, College of medicine, Chang Gung University, Tao-Yuan, Taiwan, Republic of China; Molecular

Int J Biochem Cell Biol ; 53: 55-65, 2014 Aug.

Article em En | MEDLINE | ID: mdl-24814288

Assuntos

Receptores Frizzled/genética; Proteína Quinase C-delta/biossíntese; Sarcoma/genética; Neoplasias Uterinas/genética; Subfamília B de Transportador de Cassetes de Ligação de ATP/biossíntese; Subfamília B de Transportador de Cassetes de Ligação de ATP/genética; Apoptose/efeitos dos fármacos; Linhagem Celular Tumoral; Doxorrubicina/administração & dosagem; Resistencia a Medicamentos Antineoplásicos/genética; Feminino; Receptores Frizzled/metabolismo; Regulação Neoplásica da Expressão Gênica; Humanos; Sarcoma/tratamento farmacológico; Sarcoma/patologia; Transdução de Sinais; Neoplasias Uterinas/tratamento farmacológico; Neoplasias Uterinas/patologia

Palavras-chave

Apoptosis; Cell cycle; Multiple drug resistance; PKC delta; Rottelerin; shRNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma / Neoplasias Uterinas / Proteína Quinase C-delta / Receptores Frizzled Limite: Female / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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