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LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint.
Dimitrova, Nadya; Zamudio, Jesse R; Jong, Robyn M; Soukup, Dylan; Resnick, Rebecca; Sarma, Kavitha; Ward, Amanda J; Raj, Arjun; Lee, Jeannie T; Sharp, Phillip A; Jacks, Tyler.
Afiliação
  • Dimitrova N; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02142, USA.
  • Zamudio JR; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02142, USA.
  • Jong RM; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02142, USA.
  • Soukup D; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02142, USA.
  • Resnick R; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02142, USA.
  • Sarma K; Department of Molecular Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.
  • Ward AJ; Isis Pharmaceuticals, Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA.
  • Raj A; Department of Bioengineering, University of Pennsylvania, 210 South 33rd Street, Philadelphia, PA 19104, USA.
  • Lee JT; Department of Molecular Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.
  • Sharp PA; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02142, USA.
  • Jacks T; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address: t
Mol Cell ; 54(5): 777-90, 2014 Jun 05.
Article em En | MEDLINE | ID: mdl-24857549
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidor de Quinase Dependente de Ciclina p21 / Pontos de Checagem da Fase G1 do Ciclo Celular / Proteínas do Grupo Polycomb / RNA Longo não Codificante Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidor de Quinase Dependente de Ciclina p21 / Pontos de Checagem da Fase G1 do Ciclo Celular / Proteínas do Grupo Polycomb / RNA Longo não Codificante Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article