Rous sarcoma virus synaptic complex capable of concerted integration is kinetically trapped by human immunodeficiency virus integrase strand transfer inhibitors.

Pandey, Krishan K; Bera, Sibes; Korolev, Sergey; Campbell, Mary; Yin, Zhiqi; Aihara, Hideki; Grandgenett, Duane P

Pandey, Krishan K; Bera, Sibes; Korolev, Sergey; Campbell, Mary; Yin, Zhiqi; Aihara, Hideki; Grandgenett, Duane P.

Afiliação

Pandey KK; From the Institute for Molecular Virology.
Bera S; From the Institute for Molecular Virology.
Korolev S; Department of Biochemistry and Molecular Biology.
Campbell M; Center for World Health and Medicine, Saint Louis University Health Sciences Center, Saint Louis, Missouri 63104 and.
Yin Z; the Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455.
Aihara H; the Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455.
Grandgenett DP; From the Institute for Molecular Virology, grandgdp@slu.edu.

J Biol Chem ; 289(28): 19648-58, 2014 Jul 11.

Article em En | MEDLINE | ID: mdl-24872410

Assuntos

DNA Viral/química; Integrase de HIV/química; HIV-1/química; Vírus do Sarcoma de Rous/química; DNA Viral/imunologia; Integrase de HIV/metabolismo; HIV-1/fisiologia; Humanos; Estrutura Terciária de Proteína; Vírus do Sarcoma de Rous/fisiologia; Montagem de Vírus/fisiologia

Palavras-chave

AIDS; Alpharetrovirus; Antiviral Agent; DNA-Protein Interaction; Enzyme Inhibitor; HIV-1 Protease; Integrase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Viral / HIV-1 / Integrase de HIV / Vírus do Sarcoma de Rous Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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