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Translational PK/PD modeling for cardiovascular safety assessment of drug candidates: Methods and examples in drug development.
Caruso, Antonello; Frances, Nicolas; Meille, Christophe; Greiter-Wilke, Andrea; Hillebrecht, Alexander; Lavé, Thierry.
Afiliação
  • Caruso A; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland. Electronic address: antonello.caruso@roche.com.
  • Frances N; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
  • Meille C; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
  • Greiter-Wilke A; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
  • Hillebrecht A; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
  • Lavé T; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
J Pharmacol Toxicol Methods ; 70(1): 73-85, 2014.
Article em En | MEDLINE | ID: mdl-24879942
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Sistema Cardiovascular Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Sistema Cardiovascular Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article