Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate.

Demont, Emmanuel H; Andrews, Benjamin I; Bit, Rino A; Campbell, Colin A; Cooke, Jason W B; Deeks, Nigel; Desai, Sapna; Dowell, Simon J; Gaskin, Pam; Gray, James R J; Haynes, Andrea; Holmes, Duncan S; Kumar, Umesh; Morse, Mary A; Osborne, Greg J; Panchal, Terry; Patel, Bela; Perboni, Alcide; Taylor, Simon; Watson, Robert; Witherington, Jason; Willis, Robert

Demont, Emmanuel H; Andrews, Benjamin I; Bit, Rino A; Campbell, Colin A; Cooke, Jason W B; Deeks, Nigel; Desai, Sapna; Dowell, Simon J; Gaskin, Pam; Gray, James R J; Haynes, Andrea; Holmes, Duncan S; Kumar, Umesh; Morse, Mary A; Osborne, Greg J; Panchal, Terry; Patel, Bela; Perboni, Alcide; Taylor, Simon; Watson, Robert; Witherington, Jason; Willis, Robert.

Afiliação

Demont EH; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Andrews BI; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Bit RA; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Campbell CA; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Cooke JW; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Deeks N; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Desai S; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Dowell SJ; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Gaskin P; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Gray JR; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Haynes A; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Holmes DS; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Kumar U; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Morse MA; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Osborne GJ; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Panchal T; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Patel B; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Perboni A; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Taylor S; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Watson R; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Witherington J; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
Willis R; Immuno Inflammation Center of Excellence for Drug Discovery and Platform Technology and Science, GlaxoSmithKline , Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.