Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning.

Aoki, Toshihiro; Hyohdoh, Ikumi; Furuichi, Noriyuki; Ozawa, Sawako; Watanabe, Fumio; Matsushita, Masayuki; Sakaitani, Masahiro; Morikami, Kenji; Takanashi, Kenji; Harada, Naoki; Tomii, Yasushi; Shiraki, Koji; Furumoto, Kentaro; Tabo, Mitsuyasu; Yoshinari, Kiyoshi; Ori, Kazutomo; Aoki, Yuko; Shimma, Nobuo; Iikura, Hitoshi

Aoki, Toshihiro; Hyohdoh, Ikumi; Furuichi, Noriyuki; Ozawa, Sawako; Watanabe, Fumio; Matsushita, Masayuki; Sakaitani, Masahiro; Morikami, Kenji; Takanashi, Kenji; Harada, Naoki; Tomii, Yasushi; Shiraki, Koji; Furumoto, Kentaro; Tabo, Mitsuyasu; Yoshinari, Kiyoshi; Ori, Kazutomo; Aoki, Yuko; Shimma, Nobuo; Iikura, Hitoshi.

Afiliação

Aoki T; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Hyohdoh I; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Furuichi N; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Ozawa S; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Watanabe F; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Matsushita M; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Sakaitani M; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Morikami K; Research Division, Chugai Pharmaceutical Co., Ltd. , 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.
Takanashi K; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Harada N; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Tomii Y; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Shiraki K; Research Division, Chugai Pharmaceutical Co., Ltd. , 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.
Furumoto K; Research Division, Chugai Pharmaceutical Co., Ltd. , 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.
Tabo M; Research Division, Chugai Pharmaceutical Co., Ltd. , 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.
Yoshinari K; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Ori K; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Aoki Y; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Shimma N; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan.
Iikura H; Research Division, Chugai Pharmaceutical Co., Ltd. , 200 Kajiwara, Kamakura, Kanagawa 247-8530, Japan ; Research Division, Chugai Pharmaceutical Co., Ltd. , 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.