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Characterization of Novel PI3Kδ Inhibitors as Potential Therapeutics for SLE and Lupus Nephritis in Pre-Clinical Studies.
Haselmayer, Philipp; Camps, Montserrat; Muzerelle, Mathilde; El Bawab, Samer; Waltzinger, Caroline; Bruns, Lisa; Abla, Nada; Polokoff, Mark A; Jond-Necand, Carole; Gaudet, Marilène; Benoit, Audrey; Bertschy Meier, Dominique; Martin, Catherine; Gretener, Denise; Lombardi, Maria Stella; Grenningloh, Roland; Ladel, Christoph; Petersen, Jørgen Søberg; Gaillard, Pascale; Ji, Hong.
Afiliação
  • Haselmayer P; Immunology, Department of Preclinical Pharmacology, Merck Serono , Darmstadt , Germany ; Biologics and Immunology Platform, Merck Serono , Darmstadt , Germany.
  • Camps M; Department of Cellular Immunology, Merck Serono SA , Geneva , Switzerland ; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland.
  • Muzerelle M; Department of Chemistry, Merck Serono SA , Geneva , Switzerland.
  • El Bawab S; Drug Metabolism and Pharmacokinetics (DMPK), Non-Clinical Development, Merck Serono , Darmstadt , Germany.
  • Waltzinger C; Department of Cellular Immunology, Merck Serono SA , Geneva , Switzerland ; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland.
  • Bruns L; Immunology, Department of Preclinical Pharmacology, Merck Serono , Darmstadt , Germany ; Biologics and Immunology Platform, Merck Serono , Darmstadt , Germany.
  • Abla N; Drug Metabolism and Pharmacokinetics (DMPK), Non-Clinical Development, Merck Serono SA , Geneva , Switzerland.
  • Polokoff MA; BioSeek® Division, DiscoveRx Corporation , South San Francisco, CA , USA.
  • Jond-Necand C; Department of Cellular Immunology, Merck Serono SA , Geneva , Switzerland ; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland.
  • Gaudet M; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland ; Department of Early PK/PD Biomarker, Merck Serono SA , Geneva , Switzerland.
  • Benoit A; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland ; Department of Early PK/PD Biomarker, Merck Serono SA , Geneva , Switzerland.
  • Bertschy Meier D; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland ; Department of Early PK/PD Biomarker, Merck Serono SA , Geneva , Switzerland.
  • Martin C; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland ; Department of Early PK/PD Biomarker, Merck Serono SA , Geneva , Switzerland.
  • Gretener D; Department of Screening, Merck Serono SA , Geneva , Switzerland.
  • Lombardi MS; Department of Cellular Immunology, Merck Serono SA , Geneva , Switzerland ; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland.
  • Grenningloh R; Immunology, Department of Preclinical Pharmacology, EMD Serono Research and Development Institute , Billerica, MA , USA.
  • Ladel C; Biologics and Immunology Platform, Merck Serono , Darmstadt , Germany.
  • Petersen JS; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland.
  • Gaillard P; Department of Chemistry, Merck Serono SA , Geneva , Switzerland.
  • Ji H; Biologics and Immunology Platform, Merck Serono SA , Geneva , Switzerland ; Department of Early PK/PD Biomarker, Merck Serono SA , Geneva , Switzerland.
Front Immunol ; 5: 233, 2014.
Article em En | MEDLINE | ID: mdl-24904582

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2014 Tipo de documento: Article