Similar rate of information transfer on stimulus intensity in accessory and main olfactory bulb output neurons.
Neurosci Lett
; 576: 56-61, 2014 Jul 25.
Article
em En
| MEDLINE
| ID: mdl-24909616
ABSTRACT
Recently, evidence has accumulated that the vomeronasal system cooperates with the main olfactory system to process volatile cues that regulate the animal's behavior. This is contradictory to the traditional view that the vomeronasal system is quite different from the main olfactory system in the time scale of information processing. Particularly, the firing rate of mitral/tufted cells in the accessory olfactory bulb (MTAOB) is known to be significantly lower than that of mitral cells in the main olfactory bulb (MCMOB). To address this question of whether the low-frequency firing in MTAOB carries less information than the high-frequency firing in MCMOB in the early stages of stimulation, we compared MTAOB and MCMOB for their firing mechanisms and information transfer characteristics. A model computation demonstrated that the inherent channel kinetics of MTAOB was responsible for their firing at a lower frequency than MCMOB. Nevertheless, our analysis suggested that MTAOB were comparable to MCMOB in both the amount and speed of information transfer about depolarizing current intensity immediately after current injection onset (<200ms). Our results support a hypothesis of simultaneous processing of common cues in both systems.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Bulbo Olfatório
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Canais de Potássio de Abertura Dependente da Tensão da Membrana
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Canais de Sódio Disparados por Voltagem
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Neurônios
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article