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Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells.
Drouet, Valérie; Ruiz, Marta; Zala, Diana; Feyeux, Maxime; Auregan, Gwennaëlle; Cambon, Karine; Troquier, Laetitia; Carpentier, Johann; Aubert, Sophie; Merienne, Nicolas; Bourgois-Rocha, Fany; Hassig, Raymonde; Rey, Maria; Dufour, Noëlle; Saudou, Frédéric; Perrier, Anselme L; Hantraye, Philippe; Déglon, Nicole.
Afiliação
  • Drouet V; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France.
  • Ruiz M; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France.
  • Zala D; Institut Curie, Orsay, France; UMR3306, Centre National de Recherché Scientifique (CNRS), Orsay, France; U1005, Institut National de la Santé et de la Recherche Médicale (INSERM), Orsay France.
  • Feyeux M; U861, Institut National de la Santé et de la Recherche Médicale (INSERM), AFM, Evry, France; UEVE U861, I-STEM, AFM, Evry, France.
  • Auregan G; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France.
  • Cambon K; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France.
  • Troquier L; Department of Clinical Neurosciences (DNC), Lausanne University Hospital (CHUV), Lausanne, Switzerland.
  • Carpentier J; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France.
  • Aubert S; CECS, I-STEM, AFM, Evry, France.
  • Merienne N; Department of Clinical Neurosciences (DNC), Lausanne University Hospital (CHUV), Lausanne, Switzerland.
  • Bourgois-Rocha F; U861, Institut National de la Santé et de la Recherche Médicale (INSERM), AFM, Evry, France; UEVE U861, I-STEM, AFM, Evry, France.
  • Hassig R; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France.
  • Rey M; Department of Clinical Neurosciences (DNC), Lausanne University Hospital (CHUV), Lausanne, Switzerland.
  • Dufour N; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France.
  • Saudou F; Institut Curie, Orsay, France; UMR3306, Centre National de Recherché Scientifique (CNRS), Orsay, France; U1005, Institut National de la Santé et de la Recherche Médicale (INSERM), Orsay France.
  • Perrier AL; U861, Institut National de la Santé et de la Recherche Médicale (INSERM), AFM, Evry, France; UEVE U861, I-STEM, AFM, Evry, France.
  • Hantraye P; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France.
  • Déglon N; Institute of Biomedical Imaging (I2BM) and Molecular Imaging Research Center (MIRCen), Atomic Energy Commission (CEA), Fontenay-aux-Roses, France; URA2210, Centre National de Recherché Scientifique (CNRS), Fontenay-aux-Roses, France; Department of Clinical Neurosciences (DNC), Lausanne University Ho
PLoS One ; 9(6): e99341, 2014.
Article em En | MEDLINE | ID: mdl-24926995
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Terapia Genética / Doença de Huntington / RNA Interferente Pequeno / Proteínas Mutantes / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Terapia Genética / Doença de Huntington / RNA Interferente Pequeno / Proteínas Mutantes / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article