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Parallel transmit pulse design for patients with deep brain stimulation implants.
Eryaman, Yigitcan; Guerin, Bastien; Akgun, Can; Herraiz, Joaquin L; Martin, Adrian; Torrado-Carvajal, Angel; Malpica, Norberto; Hernandez-Tamames, Juan A; Schiavi, Emanuele; Adalsteinsson, Elfar; Wald, Lawrence L.
Afiliação
  • Eryaman Y; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA; Madrid-MIT M+ Vision Consortium, Madrid, Spain.
Magn Reson Med ; 73(5): 1896-903, 2015 May.
Article em En | MEDLINE | ID: mdl-24947104
PURPOSE: Specific absorption rate (SAR) amplification around active implantable medical devices during diagnostic MRI procedures poses a potential risk for patient safety. In this study, we present a parallel transmit (pTx) strategy that can be used to safely scan patients with deep brain stimulation (DBS) implants. METHODS: We performed electromagnetic simulations at 3T using a uniform phantom and a multitissue realistic head model with a generic DBS implant. Our strategy is based on using implant-friendly modes, which are defined as the modes of an array that reduce the local SAR around the DBS lead tip. These modes are used in a spokes pulse design algorithm in order to produce highly uniform magnitude least-squares flip angle excitations. RESULTS: Local SAR (1 g) at the lead tip is reduced below 0.1 W/kg compared with 31.2 W/kg, which is obtained by a simple quadrature birdcage excitation without any sort of SAR mitigation. For the multitissue realistic head model, peak 10 g local SAR and global SAR are obtained as 4.52 W/kg and 0.48 W/kg, respectively. A uniform axial flip angle is also obtained (NRMSE <3%). CONCLUSION: Parallel transmit arrays can be used to generate implant-friendly modes and to reduce SAR around DBS implants while constraining peak local SAR and global SAR and maximizing flip angle homogeneity.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Imagens de Fantasmas / Estimulação Encefálica Profunda / Segurança de Equipamentos / Metais Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Imagens de Fantasmas / Estimulação Encefálica Profunda / Segurança de Equipamentos / Metais Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article