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The Chlamydomonas genome project: a decade on.
Blaby, Ian K; Blaby-Haas, Crysten E; Tourasse, Nicolas; Hom, Erik F Y; Lopez, David; Aksoy, Munevver; Grossman, Arthur; Umen, James; Dutcher, Susan; Porter, Mary; King, Stephen; Witman, George B; Stanke, Mario; Harris, Elizabeth H; Goodstein, David; Grimwood, Jane; Schmutz, Jeremy; Vallon, Olivier; Merchant, Sabeeha S; Prochnik, Simon.
Afiliação
  • Blaby IK; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
  • Blaby-Haas CE; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
  • Tourasse N; Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche 7141, Institut de Biologie Physico-Chimique, Paris, France.
  • Hom EF; Department of Molecular and Cellular Biology and FAS Center for Systems Biology, Harvard University, Cambridge, MA, USA.
  • Lopez D; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA, USA.
  • Aksoy M; Department of Plant Biology, Carnegie Institute for Science, 260 Panama Street, Stanford, CA, USA.
  • Grossman A; Department of Plant Biology, Carnegie Institute for Science, 260 Panama Street, Stanford, CA, USA.
  • Umen J; Donald Danforth Plant Science Center, St Louis, MO, USA.
  • Dutcher S; Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.
  • Porter M; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, USA.
  • King S; Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT, USA.
  • Witman GB; Department of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Stanke M; lnstitut für Mikrobiologie und Genetik, Universität Göttingen, Göttingen, Germany.
  • Harris EH; Department of Biology, Duke University, Durham, NC 27708, USA.
  • Goodstein D; US Department of Energy, Joint Genome Institute, Walnut Creek, CA 94598, USA.
  • Grimwood J; HudsonAlpha Genome Sequencing Center, Huntsville, AL 35806, USA.
  • Schmutz J; HudsonAlpha Genome Sequencing Center, Huntsville, AL 35806, USA.
  • Vallon O; Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche 7141, Institut de Biologie Physico-Chimique, Paris, France; Université Pierre et Marie Curie, Paris, France.
  • Merchant SS; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA; Institute of Genomics and Proteomics, University of California, Los Angeles, CA 90095, USA.
  • Prochnik S; US Department of Energy, Joint Genome Institute, Walnut Creek, CA 94598, USA. Electronic address: seprochnik@lbl.gov.
Trends Plant Sci ; 19(10): 672-80, 2014 Oct.
Article em En | MEDLINE | ID: mdl-24950814
ABSTRACT
The green alga Chlamydomonas reinhardtii is a popular unicellular organism for studying photosynthesis, cilia biogenesis, and micronutrient homeostasis. Ten years since its genome project was initiated an iterative process of improvements to the genome and gene predictions has propelled this organism to the forefront of the omics era. Housed at Phytozome, the plant genomics portal of the Joint Genome Institute (JGI), the most up-to-date genomic data include a genome arranged on chromosomes and high-quality gene models with alternative splice forms supported by an abundance of whole transcriptome sequencing (RNA-Seq) data. We present here the past, present, and future of Chlamydomonas genomics. Specifically, we detail progress on genome assembly and gene model refinement, discuss resources for gene annotations, functional predictions, and locus ID mapping between versions and, importantly, outline a standardized framework for naming genes.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chlamydomonas reinhardtii / Genoma de Planta / Genômica / Cromossomos de Plantas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chlamydomonas reinhardtii / Genoma de Planta / Genômica / Cromossomos de Plantas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2014 Tipo de documento: Article