Avanti lipid tools: connecting lipids, technology, and cell biology.
Biochim Biophys Acta
; 1841(8): 1038-48, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-24954118
Lipid research is challenging owing to the complexity and diversity of the lipidome. Here we review a set of experimental tools developed for the seasoned lipid researcher, as well as, those who are new to the field of lipid research. Novel tools for probing protein-lipid interactions, applications for lipid binding antibodies, enhanced systems for the cellular delivery of lipids, improved visualization of lipid membranes using gold-labeled lipids, and advances in mass spectrometric analysis techniques will be discussed. Because lipid mediators are known to participate in a host of signal transduction and trafficking pathways within the cell, a comprehensive lipid toolbox that aids the science of lipidomics research is essential to better understand the molecular mechanisms of interactions between cellular components. This article is part of a Special Issue entitled Tools to study lipid functions.
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MEDLINE
Assunto principal:
Lipídeos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article