Selective double disconnection for cirrhotic portal hypertension.
J Surg Res
; 192(2): 383-9, 2014 Dec.
Article
em En
| MEDLINE
| ID: mdl-24972739
ABSTRACT
BACKGROUND:
To evaluate the effect of selective double portazygous disconnection with preserving vagus (SDPDPV) for patients with portal hypertension (PHT) in the authors' hospital.METHODS:
Patients (453) with cirrhotic PHT who underwent either SDPDPV or pericardial devascularization with splenectomy (PDS) for variceal bleeding from February 2007 to January 2013 were retrospectively reviewed. The operation-relevant information, change of lavatory examination data, postoperative complications, and clinical outcomes were analyzed.RESULTS:
There were no significant difference between the SDPDPV group and the PDS group of mean operative time and intraoperative blood loss (P >0.05). The free portal pressure in the SDPDPV group was much lower than PDS group significantly after operation (P <0.05). The test of biochemical profile of hepatocyte functions and Child-Pugh score at the end of the first postoperative year were significantly more altered in the SDPDPV group than in the PDS group (P <0.05). Except encephalopathy, occurrences or development of postoperative complications including rebleeding, ascites, and gastric stasis showed great difference between the two groups (P <0.05). The operative mortality rate and the 3-y survival rates were great difference between the two groups too (P <0.05).CONCLUSIONS:
The SDPDPV not only controls recurrent bleeding from varices with PHT effectively but also maintains normal dynamics of stomach and physiological function of intestine and hepatobiliary.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Nervo Vago
/
Varizes Esofágicas e Gástricas
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Hemorragia Gastrointestinal
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Hipertensão Portal
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Cirrose Hepática
Tipo de estudo:
Etiology_studies
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Observational_studies
/
Prognostic_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article