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Discovery of acylurea isosteres of 2-acylaminothiadiazole in the azaxanthene series of glucocorticoid receptor agonists.
Gong, Hua; Yang, Michael; Xiao, Zili; Doweyko, Arthur M; Cunningham, Mark; Wang, Jinhong; Habte, Sium; Holloway, Deborah; Burke, Christine; Shuster, David; Gao, Ling; Carman, Julie; Somerville, John E; Nadler, Steven G; Salter-Cid, Luisa; Barrish, Joel C; Weinstein, David S.
Afiliação
  • Gong H; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Yang M; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Xiao Z; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Doweyko AM; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Cunningham M; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Wang J; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Habte S; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Holloway D; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Burke C; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Shuster D; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Gao L; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Carman J; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Somerville JE; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Nadler SG; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Salter-Cid L; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Barrish JC; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States.
  • Weinstein DS; Department of Discovery Chemistry, Immunoscience, Bristol-Myers Squibb Company, Research and Development, Princeton, NJ 08543-4000, United States. Electronic address: David.Weinstein@bms.com.
Bioorg Med Chem Lett ; 24(15): 3268-73, 2014 Aug 01.
Article em En | MEDLINE | ID: mdl-24980053
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiadiazóis / Ureia / Receptores de Glucocorticoides / Descoberta de Drogas / Compostos Heterocíclicos com 3 Anéis Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiadiazóis / Ureia / Receptores de Glucocorticoides / Descoberta de Drogas / Compostos Heterocíclicos com 3 Anéis Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article