A historical perspective on peripheral reflex cardiovascular control from animals to man.
Exp Physiol
; 99(8): 1017-26, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-24986973
ABSTRACT
Although drug treatment of human hypertension has greatly improved, there is renewed interest in non-drug methods of blood pressure reduction. Animal experiments have now shown that arterial baroreflexes do control long-term blood pressure levels, particularly by nervously mediated renal excretion of sodium and water. This Paton Lecture provides a review of the historical development of knowledge of peripheral circulatory control in order to supplement prior Paton Lectures concerned with cerebral cortical and other areas of influence. I also discuss how improved understanding of nervous control of the circulation has led to current methods of non-drug blood pressure control in man by implanted carotid baroreceptor pacemakers or by renal denervation. Finally, the role of other therapy, particularly listening to music, is reviewed.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sistema Cardiovascular
/
Barorreflexo
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article