[Diagnostic evaluation of ß-lactam antibiotic allergy]. / Diagnostiek van betalactamantibiotica-allergie.
Ned Tijdschr Geneeskd
; 158: A7306, 2014.
Article
em Nl
| MEDLINE
| ID: mdl-24988157
ABSTRACT
Many patients report a ß-lactam allergy or hypersensitivity without actually having this allergy. Targeted questioning, in combination with an accurate description of the nature of the symptoms, leads to rejection of a large number of these presumed allergies. In a suspected allergic reaction one has to distinguish between the potentially life-threatening, acute type I mediated allergy and delayed type IV skin reaction. The diagnostic evaluation of a suspected allergy is described in this article. Three cases are presented of a presumed allergic reaction to ß-lactam antibiotics. Patient A was a 62-year-old woman with anaphylaxis triggered by amoxicillin/clavulanate who, after analysis, was advised to avoid all ß-lactam antibiotics. Patient B was a 58-year-old man with anaphylaxis triggered by amoxicillin/clavulanate as a result of a selective allergy to amoxicillin. Patient C was a 50-year-old man who had had a possible reaction to a penicillin in his childhood. Analysis in an allergology department can be useful for further treatment.
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Base de dados:
MEDLINE
Assunto principal:
Testes Cutâneos
/
Beta-Lactamas
/
Hipersensibilidade a Drogas
/
Antibacterianos
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Nl
Ano de publicação:
2014
Tipo de documento:
Article