The role of in vivo confocal microscopy in the diagnosis of eyelid margin tumors: 47 cases.
J Am Acad Dermatol
; 71(5): 912-918.e2, 2014 Nov.
Article
em En
| MEDLINE
| ID: mdl-24998093
ABSTRACT
BACKGROUND:
Handheld in vivo reflectance confocal microscopy (IVCM) is a new imaging method that allows noninvasive diagnosis of cutaneous tumors but to date it has not been used in the study of eyelid tumors.OBJECTIVE:
We sought to evaluate the suitability of IVCM for eyelid margin tumors.METHODS:
We prospectively evaluated the IVCM features of 47 eyelid margin lesions, clinically suspicious of malignancy; 35 of these were excised whereas the other 12, with no IVCM malignant features, were followed up for at least 1 year. Clinical, IVCM, and histologic diagnoses were compared.RESULTS:
IVCM showed sensitivity and specificity of 100% and 69.2%, respectively, for malignancy (basal cell carcinoma, squamous cell carcinoma, and melanoma). The follow-up of the 12 nonexcised lesions did not show any clinical progression.LIMITATIONS:
The lesions showing neither clinical nor IVCM features for malignancies were not biopsied in view of the potential functional and aesthetic consequences of eyelid margin surgery.CONCLUSION:
Used with a handheld dermatology-specific microscope, IVCM can play a role in the noninvasive diagnosis of eyelid margin lesions. Further studies are needed to better define diagnostic criteria of eyelid tumors and improve the specificity of this technique.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
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Carcinoma Basocelular
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Carcinoma de Células Escamosas
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Microscopia Confocal
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Neoplasias da Túnica Conjuntiva
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Neoplasias Palpebrais
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Melanoma
Tipo de estudo:
Diagnostic_studies
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Observational_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article