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The impact of anti-apoptotic gene Bcl-2∆ expression on CHO central metabolism.
Templeton, Neil; Lewis, Abasha; Dorai, Haimanti; Qian, Elaine A; Campbell, Marguerite P; Smith, Kevin D; Lang, Steven E; Betenbaugh, Michael J; Young, Jamey D.
Afiliação
  • Templeton N; Department of Chemical and Biomolecular Engineering, Vanderbilt University; PMB 351604, 2301 Vanderbilt Place, Nashville, TN 37235-1604, USA.
  • Lewis A; Department of Chemical and Biomolecular Engineering, Johns Hopkins University; 3400 North Charles Street, Baltimore, MD 21218, USA.
  • Dorai H; Janssen Pharmaceutical J&J, Biologics Research, Biotechnology CoE; 1400 McKean Road, Spring House, PA, 19002 USA.
  • Qian EA; Department of Chemical and Biomolecular Engineering, Vanderbilt University; PMB 351604, 2301 Vanderbilt Place, Nashville, TN 37235-1604, USA.
  • Campbell MP; Janssen Pharmaceutical J&J, Biologics Research, Biotechnology CoE; 1400 McKean Road, Spring House, PA, 19002 USA.
  • Smith KD; Janssen Pharmaceutical J&J, Biologics Research, Biotechnology CoE; 1400 McKean Road, Spring House, PA, 19002 USA.
  • Lang SE; Janssen Pharmaceutical J&J, Biologics Research, Biotechnology CoE; 1400 McKean Road, Spring House, PA, 19002 USA.
  • Betenbaugh MJ; Department of Chemical and Biomolecular Engineering, Johns Hopkins University; 3400 North Charles Street, Baltimore, MD 21218, USA.
  • Young JD; Department of Chemical and Biomolecular Engineering, Vanderbilt University; PMB 351604, 2301 Vanderbilt Place, Nashville, TN 37235-1604, USA; Department of Molecular Physiology and Biophysics, Vanderbilt University; PMB 351604, 2301 Vanderbilt Place, Nashville, TN 37235-1604, USA. Electronic address
Metab Eng ; 25: 92-102, 2014 Sep.
Article em En | MEDLINE | ID: mdl-25014175
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Ácido Láctico / Ácido Pirúvico / Proteínas Proto-Oncogênicas c-bcl-2 / Proteínas Mitocondriais / Proteínas Reguladoras de Apoptose / Análise do Fluxo Metabólico Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Ácido Láctico / Ácido Pirúvico / Proteínas Proto-Oncogênicas c-bcl-2 / Proteínas Mitocondriais / Proteínas Reguladoras de Apoptose / Análise do Fluxo Metabólico Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article