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Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge.
Darrah, Patricia A; Bolton, Diane L; Lackner, Andrew A; Kaushal, Deepak; Aye, Pyone Pyone; Mehra, Smriti; Blanchard, James L; Didier, Peter J; Roy, Chad J; Rao, Srinivas S; Hokey, David A; Scanga, Charles A; Sizemore, Donata R; Sadoff, Jerald C; Roederer, Mario; Seder, Robert A.
Afiliação
  • Darrah PA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
  • Bolton DL; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
  • Lackner AA; Tulane National Primate Research Center, Covington, LA 70433; and.
  • Kaushal D; Tulane National Primate Research Center, Covington, LA 70433; and.
  • Aye PP; Tulane National Primate Research Center, Covington, LA 70433; and.
  • Mehra S; Tulane National Primate Research Center, Covington, LA 70433; and.
  • Blanchard JL; Tulane National Primate Research Center, Covington, LA 70433; and.
  • Didier PJ; Tulane National Primate Research Center, Covington, LA 70433; and.
  • Roy CJ; Tulane National Primate Research Center, Covington, LA 70433; and.
  • Rao SS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
  • Hokey DA; Aeras, Rockville, MD 20850.
  • Scanga CA; Aeras, Rockville, MD 20850.
  • Sizemore DR; Aeras, Rockville, MD 20850.
  • Sadoff JC; Aeras, Rockville, MD 20850.
  • Roederer M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
  • Seder RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; rseder@mail.nih.gov.
J Immunol ; 193(4): 1799-811, 2014 Aug 15.
Article em En | MEDLINE | ID: mdl-25024382
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Vacinas Sintéticas / Vacinação / Vacinas contra a Tuberculose / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Vacinas Sintéticas / Vacinação / Vacinas contra a Tuberculose / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article