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Cynomolgus monkey as a surrogate for human aldehyde oxidase metabolism of the EGFR inhibitor BIBX1382.
Hutzler, J Matthew; Cerny, Matthew A; Yang, Young-Sun; Asher, Constance; Wong, Diane; Frederick, Kosea; Gilpin, Kyle.
Afiliação
  • Hutzler JM; Boehringer-Ingelheim Pharmaceuticals Inc., Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut matt.hutzler@quintiles.com.
  • Cerny MA; Boehringer-Ingelheim Pharmaceuticals Inc., Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut.
  • Yang YS; Boehringer-Ingelheim Pharmaceuticals Inc., Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut.
  • Asher C; Boehringer-Ingelheim Pharmaceuticals Inc., Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut.
  • Wong D; Boehringer-Ingelheim Pharmaceuticals Inc., Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut.
  • Frederick K; Boehringer-Ingelheim Pharmaceuticals Inc., Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut.
  • Gilpin K; Boehringer-Ingelheim Pharmaceuticals Inc., Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut.
Drug Metab Dispos ; 42(10): 1751-60, 2014 Oct.
Article em En | MEDLINE | ID: mdl-25035284
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Orgânicos / Aldeído Oxidase / Receptores ErbB Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Orgânicos / Aldeído Oxidase / Receptores ErbB Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article