Tis7 deletion reduces survival and induces intestinal anastomotic inflammation and obstruction in high-fat diet-fed mice with short bowel syndrome.

Garcia, Amy M; Wakeman, Derek; Lu, Jianyun; Rowley, Christopher; Geisman, Taylor; Butler, Catherine; Bala, Shashi; Swietlicki, Elzbieta A; Warner, Brad W; Levin, Marc S; Rubin, Deborah C

Garcia, Amy M; Wakeman, Derek; Lu, Jianyun; Rowley, Christopher; Geisman, Taylor; Butler, Catherine; Bala, Shashi; Swietlicki, Elzbieta A; Warner, Brad W; Levin, Marc S; Rubin, Deborah C.

Afiliação

Garcia AM; Division of Pediatric Gastroenterology, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri;
Wakeman D; Department of Pediatric Surgery, Washington University School of Medicine, St. Louis, Missouri;
Lu J; Division of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri;
Rowley C; Division of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri;
Geisman T; Division of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri;
Butler C; Division of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri;
Bala S; Division of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri;
Swietlicki EA; Division of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri;
Warner BW; Department of Pediatric Surgery, Washington University School of Medicine, St. Louis, Missouri;
Levin MS; Division of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri; Department of Medicine, Veterans Affairs St. Louis Health Care System; St. Louis, Missouri; and.
Rubin DC; Division of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri; Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri drubin@dom.wustl.edu.

Am J Physiol Gastrointest Liver Physiol ; 307(6): G642-54, 2014 Sep 15.

Article em En | MEDLINE | ID: mdl-25059825

Assuntos

Dieta Hiperlipídica/efeitos adversos; Enterite/etiologia; Proteínas Imediatamente Precoces/deficiência; Obstrução Intestinal/etiologia; Intestino Delgado/metabolismo; Proteínas de Membrana/deficiência; Síndrome do Intestino Curto/complicações; Anastomose Cirúrgica; Animais; Modelos Animais de Doenças; Enterite/genética; Enterite/metabolismo; Regulação da Expressão Gênica; Proteínas Imediatamente Precoces/genética; Interleucina-6/metabolismo; Absorção Intestinal; Obstrução Intestinal/genética; Obstrução Intestinal/metabolismo; Intestino Delgado/cirurgia; Metabolismo dos Lipídeos; Proteínas de Membrana/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Síndrome do Intestino Curto/genética; Síndrome do Intestino Curto/metabolismo; Fatores de Tempo

Palavras-chave

gut inflammation; intestinal adaptation; lipid metabolism; short bowel syndrome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Intestino Curto / Proteínas Imediatamente Precoces / Enterite / Dieta Hiperlipídica / Obstrução Intestinal / Intestino Delgado / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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