Intraindividual aqueous flare comparison after implantation of hydrophobic intraocular lenses with or without a heparin-coated surface.
J Cataract Refract Surg
; 40(8): 1363-70, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-25088637
ABSTRACT
PURPOSE:
To assess the efficacy of a heparin-surface-modified (HSM) hydrophobic acrylic intraocular lens (IOL) (EC-1YH PAL) and the same IOL without heparin coating (EC-1Y-PAL) by the flare and cell intensity in the anterior chamber after uneventful cataract surgery.SETTING:
Department of Ophthalmology, Paracelsus Medical University Salzburg, Austria.DESIGN:
Comparative case series.METHODS:
Routine phacoemulsification with randomized implantation of an HSM IOL in 1 eye (HSM IOL group) and an uncoated IOL (uncoated IOL group) in the fellow eye was performed. Postoperative inflammation was assessed objectively using a laser flare-cell meter (FM-600) preoperatively as well as 1 day and 1 and 3 months postoperatively. Aqueous cells in the anterior chamber, distance visual acuities, and subjective manifest refraction were also evaluated at each visit.RESULTS:
One hundred eyes (50 patients) were enrolled. In both groups, the mean flare values increased significantly from preoperatively to 1 day postoperatively (P<.001) and nearly reached preoperative values by 3 months postoperatively. One day postoperatively, the mean flare value was statistically significantly lower in the HSM IOL group (14.92 photons per millisecond [ph/ms] ± 7.47 [SD]) than in the uncoated IOL group (mean 16.73 ± 7.81 ph/ms) (P=.04); there was no statistically significant difference between groups 1 and 3 months postoperatively (both P>.58). The HSM IOL group had a greater and quicker decrease in aqueous cells, reaching statistical significance 1 month postoperatively (P=.01).CONCLUSION:
The HSM IOL showed a significant lower inflammatory reaction in the early postoperative stage with a faster disappearance of inflammatory signs. FINANCIAL DISCLOSURE No author has a financial or proprietary interest in any material or method mentioned.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Humor Aquoso
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Heparina
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Uveíte Anterior
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Implante de Lente Intraocular
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Materiais Revestidos Biocompatíveis
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Fibrinolíticos
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Lentes Intraoculares
Tipo de estudo:
Clinical_trials
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Diagnostic_studies
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Observational_studies
Limite:
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article