Identification of 3-chloro-1,2-propandiol using molecularly imprinted composite solid-phase extraction materials.
Anal Bioanal Chem
; 406(25): 6319-27, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-25096200
ABSTRACT
A novel molecularly imprinted material based on silica microparticles was synthesized by surface polymerization with 3-chloro-1,2-propandiol (3-MCPD) as a template molecule. The molecularly imprinted polymer (MIP) was characterized by infrared spectroscopy and scanning electron microscopy. The adsorption of 3-MCPD by MIP was measured by gas chromatography with electron capture detection (GC-ECD) and an equilibrium binding experiment. Scatchard analysis revealed that the maximum apparent binding capacities of the MIP and non-imprinted polymer (NIP) were 67.64 and 23.31 µmol/g, respectively. The new adsorbent was successfully used in solid-phase extraction (SPE) to selectively enrich and determine 3-MCPD in soy sauce samples. The MIP-SPE column achieves recoveries higher than 92.7% with a relative standard deviation of less than 1.83%. The MIP-SPE-GC protocol improved the selectivity and eliminated the effects of template leakage on quantitative analysis and could be used for the determination of 3-MCPD in other complex food samples.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Propilenoglicóis
/
Extração em Fase Sólida
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article