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p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.
Dreidax, Daniel; Bannert, Steffen; Henrich, Kai-Oliver; Schröder, Christina; Bender, Sebastian; Oakes, Christopher C; Lindner, Sven; Schulte, Johannes H; Duffy, David; Schwarzl, Thomas; Saadati, Maral; Ehemann, Volker; Benner, Axel; Pfister, Stefan; Fischer, Matthias; Westermann, Frank.
Afiliação
  • Dreidax D; Division of Neuroblastoma Genomics.
  • Bannert S; Division of Neuroblastoma Genomics.
  • Henrich KO; Division of Neuroblastoma Genomics.
  • Schröder C; Division of Neuroblastoma Genomics.
  • Bender S; Division of Pediatric Neurooncology.
  • Oakes CC; Division of Epigenomics and Cancer Risk Factors.
  • Lindner S; Department of Pediatric Oncology and Hematology, University Children's Hospital, Essen, Germany.
  • Schulte JH; Department of Pediatric Oncology and Hematology, University Children's Hospital, Essen, Germany.
  • Duffy D; Systems Biology Ireland, Conway Institute of Biomolecular and Biomedical Research and School of Medicine and Medical Science, University College Dublin, Ireland.
  • Schwarzl T; Systems Biology Ireland, Conway Institute of Biomolecular and Biomedical Research and School of Medicine and Medical Science, University College Dublin, Ireland.
  • Saadati M; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Ehemann V; Department of Pathology, University of Heidelberg, Heidelberg, Germany and.
  • Benner A; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Pfister S; Division of Pediatric Neurooncology.
  • Fischer M; Department of Pediatric Oncology and Center for Molecular Medicine Cologne (CMMC), University Children's Hospital, Cologne, Germany.
  • Westermann F; Division of Neuroblastoma Genomics f.westermann@dkfz.de.
Hum Mol Genet ; 23(25): 6826-37, 2014 Dec 20.
Article em En | MEDLINE | ID: mdl-25104850

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Regulação Neoplásica da Expressão Gênica / Proteínas Oncogênicas / Inibidor de Quinase Dependente de Ciclina p19 / Neoplasias do Sistema Nervoso / Neuroblastoma / Neurônios Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Regulação Neoplásica da Expressão Gênica / Proteínas Oncogênicas / Inibidor de Quinase Dependente de Ciclina p19 / Neoplasias do Sistema Nervoso / Neuroblastoma / Neurônios Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2014 Tipo de documento: Article