Low in vitro permeability of the cyanotoxin microcystin-LR across a Caco-2 monolayer: with identification of the limiting factors using modelling.

Henri, Jerome; Huguet, Antoine; Delmas, Jean-Michel; Besson, Aurore; Sanders, Pascal; Fessard, Valerie

Henri, Jerome; Huguet, Antoine; Delmas, Jean-Michel; Besson, Aurore; Sanders, Pascal; Fessard, Valerie.

Afiliação

Henri J; ANSES - French Agency for Food, Environmental and Occupational Health & Safety, Fougères Laboratory, Fougères, France. Electronic address: jerome.henri@anses.fr.
Huguet A; ANSES - French Agency for Food, Environmental and Occupational Health & Safety, Fougères Laboratory, Fougères, France.
Delmas JM; ANSES - French Agency for Food, Environmental and Occupational Health & Safety, Fougères Laboratory, Fougères, France.
Besson A; ANSES - French Agency for Food, Environmental and Occupational Health & Safety, Fougères Laboratory, Fougères, France.
Sanders P; ANSES - French Agency for Food, Environmental and Occupational Health & Safety, Fougères Laboratory, Fougères, France.
Fessard V; ANSES - French Agency for Food, Environmental and Occupational Health & Safety, Fougères Laboratory, Fougères, France.

Toxicon ; 91: 5-14, 2014 Dec.

Article em En | MEDLINE | ID: mdl-25110175

Assuntos

Microcistinas/farmacocinética; Modelos Biológicos; Células CACO-2; Humanos; Técnicas In Vitro; Toxinas Marinhas

Palavras-chave

Apparent permeability; Caco-2 monolayer; Mathematical model; Microcystin-LR

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Microcistinas / Modelos Biológicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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