Dynamic metabolites profile of cerebral ischemia/reperfusion revealed by (1)H NMR-based metabolomics contributes to potential biomarkers.

Wang, Yun; Wang, Yi-Gang; Ma, Teng-Fei; Li, Mei; Gu, Shu-Ling

Wang, Yun; Wang, Yi-Gang; Ma, Teng-Fei; Li, Mei; Gu, Shu-Ling.

Afiliação

Wang Y; Key Laboratory of Target Drug and Clinical Application, Department of Pharmacology, Xuzhou Medical College Xuzhou, Jiangsu, China.
Wang YG; Key Laboratory of Target Drug and Clinical Application, Department of Pharmacology, Xuzhou Medical College Xuzhou, Jiangsu, China ; 215 Hospital of Shannxi Nuclear Industry Xianyang, Shannxi, China.
Ma TF; Key Laboratory of Target Drug and Clinical Application, Department of Pharmacology, Xuzhou Medical College Xuzhou, Jiangsu, China.
Li M; Key Laboratory of Target Drug and Clinical Application, Department of Pharmacology, Xuzhou Medical College Xuzhou, Jiangsu, China.
Gu SL; Key Laboratory of Target Drug and Clinical Application, Department of Pharmacology, Xuzhou Medical College Xuzhou, Jiangsu, China.

Int J Clin Exp Pathol ; 7(7): 4067-75, 2014.

Article em En | MEDLINE | ID: mdl-25120785

Assuntos

Biomarcadores/sangue; Isquemia Encefálica/metabolismo; Metabolômica/métodos; Traumatismo por Reperfusão/metabolismo; Acidente Vascular Cerebral/metabolismo; Animais; Modelos Animais de Doenças; Glicina/sangue; Espectroscopia de Ressonância Magnética; Masculino; Malonatos/sangue; Ratos; Ratos Sprague-Dawley

Palavras-chave

Metabolomic; biomarkers; glycine; ischemic stroke; malonic acid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Traumatismo por Reperfusão / Isquemia Encefálica / Acidente Vascular Cerebral / Metabolômica Tipo de estudo: Prognostic_studies / Screening_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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