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The crystal structure of netrin-1 in complex with DCC reveals the bifunctionality of netrin-1 as a guidance cue.
Finci, Lorenzo I; Krüger, Nina; Sun, Xiaqin; Zhang, Jie; Chegkazi, Magda; Wu, Yu; Schenk, Gundolf; Mertens, Haydyn D T; Svergun, Dmitri I; Zhang, Yan; Wang, Jia-Huai; Meijers, Rob.
Afiliação
  • Finci LI; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, 100871, China.
  • Krüger N; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA. 02215, USA.
  • Sun X; European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, 22607, Hamburg, Germany.
  • Zhang J; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, 100871, China.
  • Chegkazi M; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, 100871, China.
  • Wu Y; European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, 22607, Hamburg, Germany.
  • Schenk G; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, 100871, China.
  • Mertens HDT; European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, 22607, Hamburg, Germany.
  • Svergun DI; European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, 22607, Hamburg, Germany.
  • Zhang Y; European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, 22607, Hamburg, Germany.
  • Wang JH; State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, 100871, China.
  • Meijers R; PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China.
Neuron ; 83(4): 839-849, 2014 Aug 20.
Article em En | MEDLINE | ID: mdl-25123307
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Axônios / Quimiotaxia / Receptores de Superfície Celular / Proteínas Supressoras de Tumor / Fatores de Crescimento Neural Tipo de estudo: Guideline / Prognostic_studies Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Axônios / Quimiotaxia / Receptores de Superfície Celular / Proteínas Supressoras de Tumor / Fatores de Crescimento Neural Tipo de estudo: Guideline / Prognostic_studies Idioma: En Ano de publicação: 2014 Tipo de documento: Article