Suzuki-Miyaura cross-coupling reactions of unprotected haloimidazoles.
J Org Chem
; 79(18): 8871-6, 2014 Sep 19.
Article
em En
| MEDLINE
| ID: mdl-25140886
ABSTRACT
An efficient protocol for the palladium-catalyzed Suzuki-Miyaura cross-coupling reaction of unprotected haloimidazoles is reported. The relatively mild reaction conditions allow for ready access to a wide array of functionalized imidazole derivatives in good to excellent yields. The synthetic utility of this method is demonstrated by the total synthesis of nortopsentin D.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paládio
/
Hidrocarbonetos Halogenados
/
Imidazóis
/
Indóis
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article