Single expressed glycine receptor domains reconstitute functional ion channels without subunit-specific desensitization behavior.

Meiselbach, Heike; Vogel, Nico; Langlhofer, Georg; Stangl, Sabine; Schleyer, Barbara; Bahnassawy, Lamia'a; Sticht, Heinrich; Breitinger, Hans-Georg; Becker, Cord-Michael; Villmann, Carmen

Meiselbach, Heike; Vogel, Nico; Langlhofer, Georg; Stangl, Sabine; Schleyer, Barbara; Bahnassawy, Lamia'a; Sticht, Heinrich; Breitinger, Hans-Georg; Becker, Cord-Michael; Villmann, Carmen.

Afiliação

Meiselbach H; From Bioinformatics and.
Vogel N; Institute of Biochemistry, Emil Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg, Fahrstrasse 17, 91054 Erlangen, Germany.
Langlhofer G; the Institute for Clinical Neurobiology, University of Würzburg, Versbacherstrasse 5, 97078 Würzburg, Germany, and.
Stangl S; Institute of Biochemistry, Emil Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg, Fahrstrasse 17, 91054 Erlangen, Germany.
Schleyer B; the Institute for Clinical Neurobiology, University of Würzburg, Versbacherstrasse 5, 97078 Würzburg, Germany, and.
Bahnassawy L; the Biochemistry Department, German University Cairo, New Cairo City, Cairo 11835, Egypt.
Sticht H; From Bioinformatics and.
Breitinger HG; the Biochemistry Department, German University Cairo, New Cairo City, Cairo 11835, Egypt.
Becker CM; Institute of Biochemistry, Emil Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg, Fahrstrasse 17, 91054 Erlangen, Germany.
Villmann C; Institute of Biochemistry, Emil Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg, Fahrstrasse 17, 91054 Erlangen, Germany, the Institute for Clinical Neurobiology, University of Würzburg, Versbacherstrasse 5, 97078 Würzburg, Germany, and Villmann_C@ukw.de.

J Biol Chem ; 289(42): 29135-47, 2014 Oct 17.

Article em En | MEDLINE | ID: mdl-25143388

Assuntos

Canais Iônicos/química; Receptores de Glicina/química; Processamento Alternativo; Sequência de Aminoácidos; Biotinilação; Cisteína/química; Teste de Complementação Genética; Glicina/química; Células HEK293; Humanos; Dados de Sequência Molecular; Técnicas de Patch-Clamp; Ligação Proteica; Estrutura Terciária de Proteína; Homologia de Sequência de Aminoácidos

Palavras-chave

Desensitization; Domain Architecture; Glycine Receptor; Glycine Receptors; Ion Channel; Ion Channels; Neurobiology; Neurophysiology; Neurotransmitter Receptor; Patch Clamp

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Glicina / Canais Iônicos Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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