Anti-Mullerian hormone levels in American girls by age and race/ethnicity.
J Pediatr Endocrinol Metab
; 28(1-2): 189-93, 2015 Jan.
Article
em En
| MEDLINE
| ID: mdl-25153582
ABSTRACT
BACKGROUND:
Anti-Mullerian Hormone (AMH), a proposed indicator of ovarian follicle reserve in adults, has not been characterized in pediatric and adolescent females by race and/or ethnicity.OBJECTIVES:
To describe AMH levels in healthy American girls and determine the influence of age and race/ethnicity on AMH.SUBJECTS:
SUBJECTS aged 10-21 years were recruited from primary care settings and emergency departments. Race/ethnicity was characterized as White, Black or Hispanic.METHODS:
Serum for AMH levels (ng/mL) was measured using an enzyme-linked immunosorbent assay.RESULTS:
Thirty-one White, 60 Black and 24 Hispanic subjects were recruited. Mean AMH levels were 3.19 ng/mL (22.8 pmol/L) (SD 2.12) for Whites, 3.25 ng/mL (23.2 pmol/L) (SD 2.23) for Blacks and 2.97 ng/mL (21.2 pmol/L) (SD 1.75) for Hispanics. ANCOVA showed no difference in AMH levels among race/ethnicities, controlling for age (p=0.91). Age was significantly associated with AMH (p<0.001, R²=0.12).CONCLUSION:
AMH levels do not vary by race/ethnicity, and AMH levels increase with age.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Etnicidade
/
Grupos Raciais
/
Hormônio Antimülleriano
/
Reserva Ovariana
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article