Diphenylprolinol silyl ether catalyzed asymmetric Michael reaction of nitroalkanes and ß,ß-disubstituted &#945;,ß-unsaturated aldehydes for the construction of all-carbon quaternary stereogenic centers.

Hayashi, Yujiro; Kawamoto, Yuya; Honda, Masaki; Okamura, Daichi; Umemiya, Shigenobu; Noguchi, Yuka; Mukaiyama, Takasuke; Sato, Itaru

Diphenylprolinol silyl ether catalyzed asymmetric Michael reaction of nitroalkanes and ß,ß-disubstituted α,ß-unsaturated aldehydes for the construction of all-carbon quaternary stereogenic centers.

Hayashi, Yujiro; Kawamoto, Yuya; Honda, Masaki; Okamura, Daichi; Umemiya, Shigenobu; Noguchi, Yuka; Mukaiyama, Takasuke; Sato, Itaru.

Afiliação

Hayashi Y; Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki-Aza Aoba, Aoba-ku, Sendai 980-8578 (Japan). yhayashi@m.tohoku.ac.jp.

Chemistry ; 20(38): 12072-82, 2014 Sep 15.

Article em En | MEDLINE | ID: mdl-25164711

Assuntos

Alcanos/química; Éteres/química; Prolina/análogos & derivados; Aldeídos; Carbono; Catálise; Estrutura Molecular; Prolina/química; Estereoisomerismo

Palavras-chave

Michael addition; asymmetric synthesis; enantioselectivity; isomerization; organocatalysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prolina / Alcanos / Éteres Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prolina / Alcanos / Éteres Idioma: En Ano de publicação: 2014 Tipo de documento: Article