Arg287Gln variant of EPHX2 and epoxyeicosatrienoic acids are associated with insulin sensitivity in humans.

Ramirez, Claudia E; Shuey, Megan M; Milne, Ginger L; Gilbert, Kimberly; Hui, Nian; Yu, Chang; Luther, James M; Brown, Nancy J

Ramirez, Claudia E; Shuey, Megan M; Milne, Ginger L; Gilbert, Kimberly; Hui, Nian; Yu, Chang; Luther, James M; Brown, Nancy J.

Afiliação

Ramirez CE; Department of Medicine, Vanderbilt University, School of Medicine, D-3100 Medical Center North, Nashville, TN 37232, USA.
Shuey MM; Department of Medicine, Vanderbilt University, School of Medicine, D-3100 Medical Center North, Nashville, TN 37232, USA.
Milne GL; Department of Medicine, Vanderbilt University, School of Medicine, D-3100 Medical Center North, Nashville, TN 37232, USA.
Gilbert K; Department of Medicine, Vanderbilt University, School of Medicine, D-3100 Medical Center North, Nashville, TN 37232, USA.
Hui N; Department of Biostatistics, Vanderbilt University, School of Medicine, 2525 West End, Nashville, TN 37203, USA.
Yu C; Department of Biostatistics, Vanderbilt University, School of Medicine, 2525 West End, Nashville, TN 37203, USA.
Luther JM; Department of Medicine, Vanderbilt University, School of Medicine, D-3100 Medical Center North, Nashville, TN 37232, USA.
Brown NJ; Department of Medicine, Vanderbilt University, School of Medicine, D-3100 Medical Center North, Nashville, TN 37232, USA. Electronic address: Nancy.j.brown@vanderbilt.edu.

Prostaglandins Other Lipid Mediat ; 113-115: 38-44, 2014 Oct.

Article em En | MEDLINE | ID: mdl-25173047

Assuntos

Ácidos Araquidônicos/metabolismo; Epóxido Hidrolases/genética; Insulina/fisiologia; Adulto; Ácidos Araquidônicos/sangue; Índice de Massa Corporal; DNA/química; DNA/genética; Epóxido Hidrolases/metabolismo; Feminino; Variação Genética; Genótipo; Técnica Clamp de Glucose; Humanos; Insulina/metabolismo; Resistência à Insulina; Secreção de Insulina; Masculino; Pessoa de Meia-Idade; Reação em Cadeia da Polimerase; Estatísticas não Paramétricas; Adulto Jovem

Palavras-chave

Epoxyeicosatrienoic acids; Insulin sensitivity; Metabolic syndrome; Soluble epoxide hydrolase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Araquidônicos / Epóxido Hidrolases / Insulina Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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