Genetic analyses of HIV-1 pol sequences from Zimbabwean patients.
New Microbiol
; 37(3): 377-81, 2014 Jul.
Article
em En
| MEDLINE
| ID: mdl-25180853
ABSTRACT
This study analysed the sequence of HIV-1 pol gene derived from Zimbabwean infected patients. Sequence analysis, performed on 8 samples, revealed that sequences were classified as subtype C (n=5), subtype B (n=2) and CRF01_AE (n=1). Two patients, treated with a therapeutic regimen containing NRTI/NNRTI, harboured drug resistance mutations in HIV-1 DNA. Phylogenetic analysis performed on subtype C sequences showed that our strains were aggregated in different clusters depending on the country of origin.
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Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
HIV-1
/
Produtos do Gene pol do Vírus da Imunodeficiência Humana
Limite:
Adolescent
/
Adult
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
País como assunto:
Africa
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article