NOX4 mediates BMP4-induced upregulation of TRPC1 and 6 protein expressions in distal pulmonary arterial smooth muscle cells.

Jiang, Qian; Fu, Xin; Tian, Lichun; Chen, Yuqin; Yang, Kai; Chen, Xiuqing; Zhang, Jie; Lu, Wenju; Wang, Jian

Jiang, Qian; Fu, Xin; Tian, Lichun; Chen, Yuqin; Yang, Kai; Chen, Xiuqing; Zhang, Jie; Lu, Wenju; Wang, Jian.

Afiliação

Jiang Q; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Fu X; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Tian L; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Chen Y; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Yang K; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, United States of Americ
Chen X; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhang J; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Lu W; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Wang J; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, United States of Americ

PLoS One ; 9(9): e107135, 2014.

Article em En | MEDLINE | ID: mdl-25203114

Assuntos

Proteína Morfogenética Óssea 4/metabolismo; Miócitos de Músculo Liso/metabolismo; NADPH Oxidases/metabolismo; Artéria Pulmonar/metabolismo; Canais de Cátion TRPC/genética; Regulação para Cima/genética; Animais; Proteína Morfogenética Óssea 4/genética; Cálcio/metabolismo; Sinalização do Cálcio/efeitos dos fármacos; Sinalização do Cálcio/genética; Proliferação de Células/efeitos dos fármacos; Proliferação de Células/genética; Humanos; Peróxido de Hidrogênio/farmacologia; Miócitos de Músculo Liso/efeitos dos fármacos; NADPH Oxidase 4; NADPH Oxidases/genética; Artéria Pulmonar/efeitos dos fármacos; Ratos; Ratos Sprague-Dawley; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais/efeitos dos fármacos; Transdução de Sinais/genética; Canais de Cátion TRPC/metabolismo; Regulação para Cima/efeitos dos fármacos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artéria Pulmonar / Regulação para Cima / NADPH Oxidases / Miócitos de Músculo Liso / Canais de Cátion TRPC / Proteína Morfogenética Óssea 4 Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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