Atomic layer deposition coating of carbon nanotubes with aluminum oxide alters pro-fibrogenic cytokine expression by human mononuclear phagocytes in vitro and reduces lung fibrosis in mice in vivo.

Taylor, Alexia J; McClure, Christina D; Shipkowski, Kelly A; Thompson, Elizabeth A; Hussain, Salik; Garantziotis, Stavros; Parsons, Gregory N; Bonner, James C

Taylor, Alexia J; McClure, Christina D; Shipkowski, Kelly A; Thompson, Elizabeth A; Hussain, Salik; Garantziotis, Stavros; Parsons, Gregory N; Bonner, James C.

Afiliação

Taylor AJ; Environmental and Molecular Toxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.
McClure CD; Department of Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America.
Shipkowski KA; Environmental and Molecular Toxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.
Thompson EA; Environmental and Molecular Toxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.
Hussain S; Clinical Research Unit, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America.
Garantziotis S; Clinical Research Unit, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America.
Parsons GN; Department of Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America.
Bonner JC; Environmental and Molecular Toxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.

PLoS One ; 9(9): e106870, 2014.

Article em En | MEDLINE | ID: mdl-25216247

Assuntos

Óxido de Alumínio/farmacologia; Citocinas/metabolismo; Leucócitos Mononucleares/metabolismo; Nanotecnologia/métodos; Nanotubos de Carbono/química; Fagócitos/metabolismo; Animais; Morte Celular/efeitos dos fármacos; Linhagem Celular; Humanos; Inflamação/patologia; Interleucina-1beta/biossíntese; Interleucina-6/metabolismo; Leucócitos Mononucleares/efeitos dos fármacos; Pulmão/efeitos dos fármacos; Pulmão/metabolismo; Pulmão/patologia; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Macrófagos/ultraestrutura; Camundongos Endogâmicos C57BL; Nanotubos de Carbono/ultraestrutura; Osteopontina/metabolismo; Fagócitos/efeitos dos fármacos; Fibrose Pulmonar; Fuligem/farmacologia; Propriedades de Superfície; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fagócitos / Leucócitos Mononucleares / Citocinas / Nanotecnologia / Nanotubos de Carbono / Óxido de Alumínio Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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