Loss of ATP-dependent lysine uptake in the vacuolar membrane vesicles of Saccharomyces cerevisiae ypq1∆ mutant.
Biosci Biotechnol Biochem
; 78(7): 1199-202, 2014.
Article
em En
| MEDLINE
| ID: mdl-25229858
ABSTRACT
Saccharomyces cerevisiae Ypq1p is a vacuolar membrane protein of the PQ-loop protein family. We found that ATP-dependent uptake activities of amino acids by vacuolar membrane vesicles were impaired by ypq1∆ mutation. Loss of lysine uptake was most remarkable, and the uptake was recovered by overproduction of Ypq1p. Ypq1p is thus involved in transport of amino acids into vacuoles.
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Base de dados:
MEDLINE
Assunto principal:
Saccharomyces cerevisiae
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Vacúolos
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Trifosfato de Adenosina
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Proteínas de Saccharomyces cerevisiae
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Membranas Intracelulares
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Lisina
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Proteínas de Membrana
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Mutação
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article