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Group A Escherichia coli-related purpura fulminans: an unusual manifestation due to an unusual strain?
Amara, Marlène; Bonacorsi, Stéphane; Bedel, Jérôme; Mira, Jean-Paul; Laurent, Virginie; Socha, Koryna; Bruneel, Fabrice; Pangon, Béatrice; Bédos, Jean-Pierre; Grimaldi, David.
Afiliação
  • Amara M; Service de Biologie, Unité de Microbiologie, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France.
  • Bonacorsi S; IAME, UMR 1137, INSERM, Paris, France IAME, UMR 1137, Université Paris Diderot, Sorbonne Paris Cité, Paris, France Service de Microbiologie, Hôpital Robert-Debré, AP-HP, Centre National de Référence Associé Escherichia coli, Paris, France.
  • Bedel J; Service de Réanimation, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France.
  • Mira JP; Service de Réanimation, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, AP-HP, Paris, France.
  • Laurent V; Service de Réanimation, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France.
  • Socha K; Service d'Anatomo-Pathologie, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France.
  • Bruneel F; Service de Réanimation, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France.
  • Pangon B; Service de Biologie, Unité de Microbiologie, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France.
  • Bédos JP; Service de Réanimation, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France.
  • Grimaldi D; Service de Réanimation, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France dgrimaldi@ch-versailles.fr.
J Clin Microbiol ; 52(12): 4404-6, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25232165
We describe an exceptional case of life-threatening group A Escherichia coli-induced purpura fulminans. Genotyping of common polymorphisms in genes involved in innate immunity or coagulation did not reveal known susceptibility to such a manifestation. Genetic analysis of the strain revealed an unusual conserved virulence plasmidic region, pointing out its potential virulence.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escherichia coli / Infecções por Escherichia coli / Púrpura Fulminante Limite: Female / Humans / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escherichia coli / Infecções por Escherichia coli / Púrpura Fulminante Limite: Female / Humans / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article