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Development of a high-throughput screening-compatible assay to identify inhibitors of the CK2α/CK2ß interaction.
Hochscherf, Jennifer; Lindenblatt, Dirk; Steinkrüger, Michaela; Yoo, Eungyoung; Ulucan, Özlem; Herzig, Stefan; Issinger, Olaf-Georg; Helms, Volkhard; Götz, Claudia; Neundorf, Ines; Niefind, Karsten; Pietsch, Markus.
Afiliação
  • Hochscherf J; Institute of Biochemistry, Department of Chemistry, University of Cologne, D-50674 Cologne, Germany; KinaseDetect ApS, DK-5220 Odense, Denmark.
  • Lindenblatt D; Institute of Biochemistry, Department of Chemistry, University of Cologne, D-50674 Cologne, Germany.
  • Steinkrüger M; Institute of Pharmacology, University Hospital of Cologne, D-50931 Cologne, Germany.
  • Yoo E; Institute of Biochemistry, Department of Chemistry, University of Cologne, D-50674 Cologne, Germany.
  • Ulucan Ö; Center for Bioinformatics, Saarland University, D-66041 Saarbrücken, Germany.
  • Herzig S; Institute of Pharmacology, University Hospital of Cologne, D-50931 Cologne, Germany.
  • Issinger OG; KinaseDetect ApS, DK-5220 Odense, Denmark; Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense, Denmark.
  • Helms V; Center for Bioinformatics, Saarland University, D-66041 Saarbrücken, Germany.
  • Götz C; Medical Biochemistry, Saarland University, D-66421 Homburg, Germany.
  • Neundorf I; Institute of Biochemistry, Department of Chemistry, University of Cologne, D-50674 Cologne, Germany. Electronic address: ines.neundorf@uni-koeln.de.
  • Niefind K; Institute of Biochemistry, Department of Chemistry, University of Cologne, D-50674 Cologne, Germany. Electronic address: karsten.niefind@uni-koeln.de.
  • Pietsch M; Institute of Pharmacology, University Hospital of Cologne, D-50931 Cologne, Germany. Electronic address: markus.pietsch@uk-koeln.de.
Anal Biochem ; 468: 4-14, 2015 01 01.
Article em En | MEDLINE | ID: mdl-25233003

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article