Pleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human.

Kushwah, Rahul; Guezguez, Borhane; Lee, Jung Bok; Hopkins, Claudia I; Bhatia, Mickie

Kushwah, Rahul; Guezguez, Borhane; Lee, Jung Bok; Hopkins, Claudia I; Bhatia, Mickie.

Afiliação

Kushwah R; McMaster Stem Cell and Cancer Research Institute (SCC-RI), Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Guezguez B; McMaster Stem Cell and Cancer Research Institute (SCC-RI), Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Lee JB; McMaster Stem Cell and Cancer Research Institute (SCC-RI), Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Hopkins CI; McMaster Stem Cell and Cancer Research Institute (SCC-RI), Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Bhatia M; McMaster Stem Cell and Cancer Research Institute (SCC-RI), Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada mbhatia@mcmaster.ca.

EMBO Rep ; 15(11): 1128-38, 2014 Nov.

Article em En | MEDLINE | ID: mdl-25252682

Assuntos

Pleiotropia Genética; Hematopoese; Leucemia/metabolismo; Receptores Notch/genética; Transdução de Sinais; Humanos; Leucemia/genética; Receptores Notch/metabolismo

Palavras-chave

Notch; hematopoiesis; human pluripotent stem cells; leukemia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Leucemia / Receptores Notch / Pleiotropia Genética / Hematopoese Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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