Poly-guanidinoethylphenylethers organised around a benzene ring: synthesis and evaluation of their antibacterial and cytotoxic properties.
Bioorg Med Chem Lett
; 24(20): 4791-3, 2014 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-25257200
ABSTRACT
A new family of poly-guanidinium species with a benzene core as the organising agent has been developed. Their antibacterial properties have been evaluated against reference Gram positive and Gram negative bacteria, and their cytotoxicity against eukaryotic cells. Most of these compounds exhibited Minimum Inhibitory Concentrations in the micromolar range.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Éteres Fenílicos
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Derivados de Benzeno
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Guanidina
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Citotoxinas
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Bactérias Gram-Negativas
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Bactérias Gram-Positivas
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Antibacterianos
Limite:
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article