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Rhesus monkey model for concurrent analyses of in vivo selectivity, pharmacokinetics and pharmacodynamics of aldosterone synthase inhibitors.
Cai, Tian-Quan; Stribling, Sloan; Tong, Xinchun; Xu, Ling; Wisniewski, Thomas; Fontenot, Jane A; Struthers, Mary; Akinsanya, Karen O.
Afiliação
  • Cai TQ; In Vivo Pharmacology, Kenilworth, NJ, USA. Electronic address: tianquan_cai@merck.com.
  • Stribling S; In Vivo Pharmacology, Kenilworth, NJ, USA.
  • Tong X; Pharmacokinetics and Drug Metabolism, Kenilworth, NJ, USA.
  • Xu L; Pharmacokinetics and Drug Metabolism, Kenilworth, NJ, USA.
  • Wisniewski T; Cardiovascular Diseases of Merck Research Laboratories, Kenilworth, NJ, USA.
  • Fontenot JA; New Iberia Primate Research Center, New Iberia, LA, USA.
  • Struthers M; Cardiovascular Diseases of Merck Research Laboratories, Kenilworth, NJ, USA.
  • Akinsanya KO; Cardiovascular Diseases of Merck Research Laboratories, Kenilworth, NJ, USA.
J Pharmacol Toxicol Methods ; 71: 137-46, 2015.
Article em En | MEDLINE | ID: mdl-25304940
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP11B2 / Modelos Animais / Inibidores Enzimáticos Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP11B2 / Modelos Animais / Inibidores Enzimáticos Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article