Identification and structural analysis of an L-asparaginase enzyme from guinea pig with putative tumor cell killing properties.

Schalk, Amanda M; Nguyen, Hien-Anh; Rigouin, Coraline; Lavie, Arnon

Schalk, Amanda M; Nguyen, Hien-Anh; Rigouin, Coraline; Lavie, Arnon.

Afiliação

Schalk AM; From the Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois 60607.
Nguyen HA; From the Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois 60607.
Rigouin C; From the Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois 60607.
Lavie A; From the Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois 60607 lavie@uic.edu.

J Biol Chem ; 289(48): 33175-86, 2014 Nov 28.

Article em En | MEDLINE | ID: mdl-25320094

Assuntos

Antineoplásicos/química; Asparaginase/química; Animais; Antineoplásicos/uso terapêutico; Asparaginase/genética; Asparaginase/uso terapêutico; Proteínas de Bactérias/química; Proteínas de Bactérias/genética; Proteínas de Bactérias/uso terapêutico; Cristalografia por Raios X; Cobaias; Humanos; Proteínas Recombinantes; Homologia Estrutural de Proteína

Palavras-chave

Anticancer Drug; Asparaginase; Cancer; Cancer Therapy; Crystallography; Enzyme Kinetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asparaginase / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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