Size-dependent patterns in depolarization maps from turbid medium and tissue.

ABSTRACT

Mueller matrix measurements on turbid media can be used to quantify its polarization properties in terms of retardance, diattenuation, and depolarization. In particular, the depolarizing ability of such media, which is represented by the depolarization index, has been shown to be a useful diagnostic parameter. However, being a single valued metric, its dependence on a host of tissue optical parameters makes it difficult to interpret. In this paper, we show that a map of depolarization as a function of input polarization state parameters can be used to infer information about the size of scatterer and order of birefringent and depolarizing layers in turbid medium. The experiments carried out on different mice organ tissues indicate that the depolarization characteristics of tissue are closely represented by depolarization properties of intralipid. We also observed that these maps do not vary in the presence of absorption.