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Mutant PIK3CA controls DUSP1-dependent ERK 1/2 activity to confer response to AKT target therapy.
Sathe, A; Guerth, F; Cronauer, M V; Heck, M M; Thalgott, M; Gschwend, J E; Retz, M; Nawroth, R.
Afiliação
  • Sathe A; Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, Munich 81675, Germany.
  • Guerth F; Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, Munich 81675, Germany.
  • Cronauer MV; Department of Urology, Ulm University Medical Center, Prittwitzstrasse 43, Ulm 89075, Germany.
  • Heck MM; Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, Munich 81675, Germany.
  • Thalgott M; Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, Munich 81675, Germany.
  • Gschwend JE; Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, Munich 81675, Germany.
  • Retz M; Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, Munich 81675, Germany.
  • Nawroth R; Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, Munich 81675, Germany.
Br J Cancer ; 111(11): 2103-13, 2014 Nov 25.
Article em En | MEDLINE | ID: mdl-25349966
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Fosfatidilinositol 3-Quinases / MAP Quinases Reguladas por Sinal Extracelular / Proteínas Proto-Oncogênicas c-akt / Fosfatase 1 de Especificidade Dupla / Compostos Heterocíclicos com 3 Anéis / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Fosfatidilinositol 3-Quinases / MAP Quinases Reguladas por Sinal Extracelular / Proteínas Proto-Oncogênicas c-akt / Fosfatase 1 de Especificidade Dupla / Compostos Heterocíclicos com 3 Anéis / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article