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Demethyleneberberine, a natural mitochondria-targeted antioxidant, inhibits mitochondrial dysfunction, oxidative stress, and steatosis in alcoholic liver disease mouse model.
Zhang, Pengcheng; Qiang, Xiaoyan; Zhang, Miao; Ma, Dongshen; Zhao, Zheng; Zhou, Cuisong; Liu, Xie; Li, Ruiyan; Chen, Huan; Zhang, Yubin.
Afiliação
  • Zhang P; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Qiang X; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Zhang M; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Ma D; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Zhao Z; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Zhou C; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Liu X; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Li R; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Chen H; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.
  • Zhang Y; State Key Laboratory of Natural Medicines, Department of Biochemistry, China Pharmaceutical University, Nanjing, China; and Institute of Toxicology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China ybzhang@cpu.edu.cn.
J Pharmacol Exp Ther ; 352(1): 139-47, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25362106
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Berberina / Estresse Oxidativo / Hepatopatias Alcoólicas / Mitocôndrias / Antioxidantes Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Berberina / Estresse Oxidativo / Hepatopatias Alcoólicas / Mitocôndrias / Antioxidantes Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article