Signs of genomic battles in mouse sex chromosomes.
Cell
; 159(4): 716-8, 2014 Nov 06.
Article
em En
| MEDLINE
| ID: mdl-25417148
ABSTRACT
Y chromosomes are challenged by a lack of recombination and are transmitted to the next generation only via males. Sequencing of the mouse Y reveals how these properties drive opposing evolutionary processes massive decay of ancestral genes and convergent acquisition and amplification of spermatid-expressed gene families on the X and Y chromosome. The convergent acquisition and amplification of X-linked paralogs on the Y maintains a surprisingly gene-rich, euchromatic mammalian male chromosome.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cromossomo Y
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Análise de Sequência de DNA
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Cromossomos de Mamíferos
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Evolução Biológica
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Camundongos Endogâmicos C57BL
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article